Homo sapiens Protein: PPAP2A
Summary
InnateDB Protein IDBP-21175.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPAP2A
Protein Name phosphatidic acid phosphatase type 2A
Synonyms LLP1a; LPP1; PAP-2a; PAP2;
Species Homo sapiens
Ensembl Protein ENSP00000264775
InnateDB Gene IDBG-21171 (PPAP2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008195 phosphatidate phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0006629 lipid metabolic process
GO:0006665 sphingolipid metabolic process
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008285 negative regulation of cell proliferation
GO:0008354 germ cell migration
GO:0019216 regulation of lipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0044281 small molecule metabolic process
GO:0046839 phospholipid dephosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
PFAM PF01569
PRINTS
PIRSF
SMART SM00014
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14494
PhosphoSite PhosphoSite-O14494
TrEMBL A0A024QZU7
UniProt Splice Variant
Entrez Gene 8611
UniGene
RefSeq NP_795714
HUGO HGNC:9228
OMIM 607124
CCDS CCDS34160
HPRD 06178
IMGT
EMBL AB000888 AC010480 AC025777 AF014402 AF014403 AF017116 BC039847 BC117133 BC143281 CH471123 Y14436
GenPept AAC16032 AAC16033 AAC32041 AAH39847 AAI17134 AAI43282 BAA22593 CAC14588 EAW54920 EAW54922 EAW54923