InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pkig

Summary

InnateDB Protein

IDBP-211953.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pkig

Protein Name

protein kinase inhibitor, gamma

Synonyms

PKIgamma;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096704

InnateDB Gene

IDBG-211949 (Pkig)

Protein Structure

UniProt Annotation

Function

Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004862	cAMP-dependent protein kinase inhibitor activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006469	negative regulation of protein kinase activity
GO:0007165	signal transduction
GO:0042308	negative regulation of protein import into nucleus
GO:0071901	negative regulation of protein serine/threonine kinase activity