InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MGP

Summary

InnateDB Protein

IDBP-21293.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MGP

Protein Name

matrix Gla protein

Synonyms

MGLAP; NTI;

Species

Homo sapiens

Ensembl Protein

ENSP00000228938

InnateDB Gene

IDBG-21291 (MGP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0005509	calcium ion binding
GO:0008147	structural constituent of bone

Biological Process

GO:0001502	cartilage condensation
GO:0001503	ossification
GO:0030154	cell differentiation
GO:0030500	regulation of bone mineralization

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
IPR002384 Osteocalcin/matrix Gla protein

PFAM

PF00594

PRINTS

PR00001
PR00002

PIRSF

SMART

SM00069

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P08493

PhosphoSite

PhosphoSite-P08493

TrEMBL

UniProt Splice Variant

Entrez Gene

4256

UniGene

RefSeq

NP_001177768

HUGO

HGNC:7060

OMIM

154870

CCDS

CCDS53752

HPRD

01112

IMGT

EMBL

AC007655 AK312029 AY542304 BC005272 BC070314 BC093078 BT006733 CH471094 CR450358 DQ004248 M55270 M58549 X07362 X53331

GenPept

AAB53765 AAB53766 AAH05272 AAH70314 AAH93078 AAP35379 AAT08173 AAY16978 BAG34966 CAA30287 CAA37418 CAG29354 EAW96333