InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sall4

Summary

InnateDB Protein

IDBP-213172.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sall4

Protein Name

sal-like 4 (Drosophila)

Synonyms

5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; Tex20;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029061

InnateDB Gene

IDBG-213166 (Sall4)

Protein Structure

UniProt Annotation

Function

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	63 [view]
Protein-Protein	62 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0001833	inner cell mass cell proliferation
GO:0001843	neural tube closure
GO:0003281	ventricular septum development
GO:0006351	transcription, DNA-templated
GO:0007507	heart development
GO:0009888	tissue development
GO:0019827	stem cell maintenance
GO:0021915	neural tube development
GO:0030326	embryonic limb morphogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter