InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Sall4

Summary

InnateDB Gene

IDBG-213166.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sall4

Gene Name

sal-like 4 (Drosophila)

Synonyms

5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; Tex20

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027547

Encoded Proteins

IDBP-213168

sal-like 4 (Drosophila)

IDBP-213172

sal-like 4 (Drosophila)

IDBP-213174

sal-like 4 (Drosophila)

IDBP-535951

sal-like 4 (Drosophila)

IDBP-531992

sal-like 4 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101115:
The protein encoded by this gene may be a zinc finger transcription factor. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:168748332-168767943

Strand

Reverse strand

Band

Transcripts

ENSMUST00000103074	ENSMUSP00000099363
ENSMUST00000029061	ENSMUSP00000029061
ENSMUST00000075044	ENSMUSP00000074556
ENSMUST00000150588	ENSMUSP00000119628
ENSMUST00000137536	ENSMUSP00000115646
ENSMUST00000125138
ENSMUST00000130640

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	63 [view]
Protein-Protein	62 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0001833	inner cell mass cell proliferation
GO:0001843	neural tube closure
GO:0003281	ventricular septum development
GO:0006351	transcription, DNA-templated
GO:0007507	heart development
GO:0009888	tissue development
GO:0019827	stem cell maintenance
GO:0021915	neural tube development
GO:0030326	embryonic limb morphogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm
GO:0043234	protein complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000101115

View Gene Order

ENSBTAG00000003101

Not yet available

Pathways

NETPATH

REACTOME

REACT_216222

Transcriptional regulation of pluripotent stem cells pathway

REACT_188576

Developmental Biology pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_111045

Developmental Biology pathway

REACT_200812

Transcriptional regulation of pluripotent stem cells pathway

KEGG

INOH

PID NCI

betacatenin_nuc_pathway

Regulation of nuclear beta catenin signaling and target gene transcription

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.434054 Mm.490784

RefSeq

NM_175303 NM_201395 NM_201396 XM_006500486

OMIM

CCDS

CCDS17115 CCDS17116 CCDS17117

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas