InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lgals3bp

Summary

InnateDB Protein

IDBP-214640.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lgals3bp

Protein Name

lectin, galactoside-binding, soluble, 3 binding protein

Synonyms

90K; CyCAP; MAC-2BP; Ppicap; Tango10b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035579

InnateDB Gene

IDBG-214638 (Lgals3bp)

Protein Structure

UniProt Annotation

Function

Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:8119883}.

Disease Associations

Tissue Specificity

Detected in embryo, liver, spleen, kidney, lung, heart, intestine, thymus and lymph node. {ECO:0000269PubMed:8119883, ECO:0000269PubMed:8341703}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005044	scavenger receptor activity
GO:0005515	protein binding

Biological Process

GO:0006898	receptor-mediated endocytosis
GO:0007155	cell adhesion

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0016020	membrane
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle