Homo sapiens Protein: BCL2L13
Summary
InnateDB Protein IDBP-229773.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L13
Protein Name BCL2-like 13 (apoptosis facilitator)
Synonyms BCL-RAMBO; Bcl2-L-13; MIL1;
Species Homo sapiens
Ensembl Protein ENSP00000382682
InnateDB Gene IDBG-1018 (BCL2L13)
Protein Structure
UniProt Annotation
Function May promote the activation of caspase-3 and apoptosis.
Subcellular Localization Isoform 2: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000305}.Isoform 1: Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
Biological Process
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0042981 regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro IPR002475 Bcl2-like
IPR026298 Blc2 family
PFAM PF00452
PRINTS PR01862
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXK5
PhosphoSite PhosphoSite-Q9BXK5
TrEMBL
UniProt Splice Variant
Entrez Gene 23786
UniGene Hs.743849
RefSeq
HUGO HGNC:17164
OMIM
CCDS
HPRD 09822
IMGT
EMBL AC006285 AF146568 AF183411 AF246665 AF325209 AK056248 AL133029 BC007658 BC016037 CR456521
GenPept AAF03602 AAG09680 AAH07658 AAH16037 AAK15150 AAK27358 BAG51659 CAB61361 CAG30407