Homo sapiens Gene: BCL2L13
Summary
InnateDB Gene IDBG-1018.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L13
Gene Name BCL2-like 13 (apoptosis facilitator)
Synonyms BCL-RAMBO; Bcl2-L-13; MIL1;
Species Homo sapiens
Ensembl Gene ENSG00000099968
Encoded Proteins
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
BCL2-like 13 (apoptosis facilitator)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:17628855-17730855
Strand Forward strand
Band q11.21
Transcripts
ENST00000317582 ENSP00000318883
ENST00000355028 ENSP00000347133
ENST00000337612 ENSP00000338932
ENST00000399782 ENSP00000382682
ENST00000399781
ENST00000399777 ENSP00000382677
ENST00000418951 ENSP00000410019
ENST00000498133 ENSP00000436321
ENST00000464649
ENST00000493680 ENSP00000434764
ENST00000479296
ENST00000485631
ENST00000538149 ENSP00000441344
ENST00000543133 ENSP00000437667
ENST00000611738 ENSP00000477967
ENST00000616863 ENSP00000480014
ENST00000618481 ENSP00000480836
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
Biological Process
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0042981 regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q9BXK5
TrEMBL
UniProt Splice Variant
Entrez Gene 23786
UniGene Hs.604999 Hs.627270 Hs.743849
RefSeq NM_001270726 NM_001270727 NM_001270728 NM_001270729 NM_001270730 NM_001270731 NM_001270732 NM_001270733 NM_001270734 NM_001270735 NM_015367 XM_006724075
HUGO HGNC:17164
OMIM
CCDS CCDS13746 CCDS59447 CCDS59448 CCDS74810 CCDS74811 CCDS74812 CCDS74813 CCDS74814
HPRD 09822
IMGT
EMBL AC006285 AF146568 AF183411 AF246665 AF325209 AK056248 AL133029 BC007658 BC016037 CR456521
GenPept AAF03602 AAG09680 AAH07658 AAH16037 AAK15150 AAK27358 BAG51659 CAB61361 CAG30407
RNA Seq Atlas 23786