InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RBBP8

Summary

InnateDB Protein

IDBP-229946.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBBP8

Protein Name

retinoblastoma binding protein 8

Synonyms

COM1; CTIP; JWDS; RIM; SAE2; SCKL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000382630

InnateDB Gene

IDBG-1496 (RBBP8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 65 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	65 [view]
Protein-Protein	62 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000014	single-stranded DNA endodeoxyribonuclease activity
GO:0001103	RNA polymerase II repressing transcription factor binding
GO:0001106	RNA polymerase II transcription corepressor activity
GO:0003684	damaged DNA binding
GO:0005515	protein binding

Biological Process

GO:0000075	cell cycle checkpoint
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000724	double-strand break repair via homologous recombination
GO:0000737	DNA catabolic process, endonucleolytic
GO:0006281	DNA repair
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007067	mitotic nuclear division
GO:0007126	meiotic nuclear division
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
GO:0031572	G2 DNA damage checkpoint