InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RCAN1

Summary

InnateDB Protein

IDBP-231030.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RCAN1

Protein Name

regulator of calcineurin 1

Synonyms

ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1;

Species

Homo sapiens

Ensembl Protein

ENSP00000382214

InnateDB Gene

IDBG-2768 (RCAN1)

Protein Structure

UniProt Annotation

Function

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

Subcellular Localization

Disease Associations

Tissue Specificity

Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0007417	central nervous system development
GO:0008015	blood circulation
GO:0019722	calcium-mediated signaling
GO:0045087	innate immune response (InnateDB)