Version 5.4
Homo sapiens Protein: KIF2A
Summary
InnateDB Protein IDBP-23200.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF2A
Protein Name kinesin heavy chain member 2A
Synonyms CDCBM3; HK2; KIF2;
Species Homo sapiens
Ensembl Protein ENSP00000370493
InnateDB Gene IDBG-23198 (KIF2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007018 microtubule-based movement
GO:0007052 mitotic spindle organization
GO:0007067 mitotic nuclear division
GO:0007399 nervous system development
GO:0007596 blood coagulation
GO:0008152 metabolic process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030154 cell differentiation
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005876 spindle microtubule
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PRINTS PR00380
PIRSF
SMART SM00129
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00139
PhosphoSite PhosphoSite-O00139
TrEMBL D6RD93
UniProt Splice Variant
Entrez Gene 3796
UniGene Hs.653858
RefSeq NP_001230881
HUGO HGNC:6318
OMIM 602591
CCDS CCDS58949
HPRD 03996
IMGT
EMBL AC016637 AC034242 AC114982 AK302270 AY317140 BC031828 CH471137 EF560716 EF560728 Y08319
GenPept AAH31828 AAP84320 ABQ59026 ABQ59038 BAG63616 CAA69621 EAW51388 EAW51390

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca