InnateDB Protein
|
IDBP-233411.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
GGT5
|
Protein Name
|
gamma-glutamyltransferase 5
|
Synonyms
|
GGT-REL; GGTLA1;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000381340
|
InnateDB Gene
|
IDBG-2783 (GGT5)
|
Protein Structure
|
|
Function |
Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4).
|
Subcellular Localization |
Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0003840
|
gamma-glutamyltransferase activity
|
GO:0036374
|
glutathione hydrolase activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000101
Gamma-glutamyltranspeptidase
IPR029055
Nucleophile aminohydrolases, N-terminal
|
PFAM |
PF01019
|
PRINTS |
PR01210
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P36269
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
2687
|
UniGene |
Hs.437156
|
RefSeq |
NP_001093251
|
HUGO |
HGNC:4260
|
OMIM |
137168
|
CCDS |
CCDS42990
|
HPRD |
00666
|
IMGT |
|
EMBL |
AK292006
AL117414
AP000353
AP000354
BC011362
BC073999
BT009808
CH471095
CT841518
M64099
|
GenPept |
AAA58503
AAH11362
AAH73999
AAP88810
BAF84695
CAB55910
CAJ86448
EAW59643
|
|
|