InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FBXO7

Summary

InnateDB Protein

IDBP-235369.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FBXO7

Protein Name

F-box protein 7

Synonyms

FBX; FBX07; FBX7; PARK15; PKPS;

Species

Homo sapiens

Ensembl Protein

ENSP00000380571

InnateDB Gene

IDBG-5164 (FBXO7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.

Experimentally validated
Total	32 [view]
Protein-Protein	31 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding

Biological Process

GO:0000422	mitochondrion degradation
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006626	protein targeting to mitochondrion
GO:0008219	cell death
GO:0016567	protein ubiquitination
GO:0031647	regulation of protein stability

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001810 F-box domain
IPR021625 Fbxo7/PI31 domain

PFAM

PF00646
PF12937
PF13013
PF11566

PRINTS

PIRSF

SMART

SM00256

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y3I1

PhosphoSite

PhosphoSite-Q9Y3I1

TrEMBL

A2A282

UniProt Splice Variant

Entrez Gene

25793

UniGene

Hs.736991

RefSeq

NP_001244919

HUGO

HGNC:13586

OMIM

605648

CCDS

CCDS58806

HPRD

07292

IMGT

EMBL

AF129537 AF233225 AK297841 AK301716 AL021937 AL035068 AL050254 BC008361 CR456491 Z71183

GenPept

AAF04471 AAF67155 AAH08361 BAG60175 BAG63187 CAB43356 CAG30377 CAI18782 CAI18783 CAI19333 CAI19334 CAI19587 CAI19588