Version 5.4
Homo sapiens Protein: RBAK
Summary
InnateDB Protein IDBP-236509.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBAK
Protein Name RB-associated KRAB zinc finger
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000380120
InnateDB Gene IDBG-7390 (RBAK)
Protein Structure
UniProt Annotation
Function May repress E2F-dependent transcription. May promote AR- dependent transcription. {ECO:0000269PubMed:10702291, ECO:0000269PubMed:14664718}.
Subcellular Localization Nucleus {ECO:0000269PubMed:10702291}.
Disease Associations
Tissue Specificity Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. {ECO:0000269PubMed:10702291}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NYW8
PhosphoSite PhosphoSite-Q9NYW8
TrEMBL
UniProt Splice Variant
Entrez Gene 57786
UniGene Hs.733005
RefSeq NP_066986
HUGO HGNC:17680
OMIM 608191
CCDS CCDS5337
HPRD
IMGT
EMBL AC008167 AC092032 AF226869 AK293069 BC136675 BC136676 BM929719 CH471144
GenPept AAF43389 AAI36676 AAI36677 AAQ93364 BAF85758 EAW87321

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca