InnateDB Protein
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IDBP-236942.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TPI1
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Protein Name
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triosephosphate isomerase 1
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Synonyms
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HEL-S-49; TIM; TPI; TPID;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000379933
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InnateDB Gene
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IDBG-15360 (TPI1)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
Triosephosphate isomerase deficiency (TPID) [MIM:615512]: An autosomal recessive multisystem disorder characterized by congenital hemolytic anemia, progressive neuromuscular dysfunction, susceptibility to bacterial infection, and cardiomyopathy. {ECO:0000269PubMed:2876430, ECO:0000269PubMed:8503454, ECO:0000269PubMed:8571957, ECO:0000269PubMed:9338582, ECO:0000269Ref.31}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
43
[view]
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Protein-Protein |
43
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000652
Triosephosphate isomerase
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PFAM |
PF00121
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P60174
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PhosphoSite |
PhosphoSite-P60174
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TrEMBL |
V9HWK1
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UniProt Splice Variant |
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Entrez Gene |
7167
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UniGene |
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RefSeq |
NP_000356
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HUGO |
HGNC:12009
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OMIM |
190450
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CCDS |
CCDS8566
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HPRD |
01833
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IMGT |
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EMBL |
AK298809
AK313282
BC007086
BC007812
BC009329
BC011611
BC015100
BC017165
BC017917
BC070129
CH471116
CR541702
EU794668
J04603
M10036
U47924
X69723
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GenPept |
AAB51316
AAB59511
AAH07086
AAH07812
AAH09329
AAH11611
AAH15100
AAH17165
AAH17917
AAH70129
AAN86636
ACJ13722
BAG36090
BAH12874
CAA49379
CAG46503
EAW88722
EAW88723
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