InnateDB Protein
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IDBP-238278.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FKBP3
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Protein Name
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FK506 binding protein 3, 25kDa
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Synonyms
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FKBP-25; FKBP-3; FKBP25; PPIase;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000379374
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InnateDB Gene
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IDBG-5577 (FKBP3)
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Protein Structure
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Function |
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
43
[view]
|
Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001179
Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
IPR013750
GHMP kinase, C-terminal domain
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PFAM |
PF00254
PF08544
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q00688
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PhosphoSite |
PhosphoSite-Q00688
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
2287
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UniGene |
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RefSeq |
NP_002004
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HUGO |
HGNC:3719
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OMIM |
186947
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CCDS |
CCDS9683
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HPRD |
01743
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IMGT |
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EMBL |
AK311915
BC016288
BC020809
BT006904
CH471078
M90309
M90820
M96256
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GenPept |
AAA58471
AAA58474
AAA58475
AAH16288
AAH20809
AAP35550
BAG34856
EAW65785
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