Homo sapiens Protein: MDK
Summary
InnateDB Protein IDBP-239297.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MDK
Protein Name midkine (neurite growth-promoting factor 2)
Synonyms ARAP; MK; NEGF2;
Species Homo sapiens
Ensembl Protein ENSP00000378936
InnateDB Gene IDBG-41723 (MDK)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0008201 heparin binding
Biological Process
GO:0007165 signal transduction
GO:0007219 Notch signaling pathway
GO:0007399 nervous system development
GO:0009611 response to wounding
GO:0030154 cell differentiation
GO:0030325 adrenal gland development
GO:0051781 positive regulation of cell division
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000762 Midkine heparin-binding growth factor
IPR020090 Pleiotrophin/Midkine, C-terminal domain
IPR020091 Pleiotrophin/Midkine disulphide-rich domain
PFAM PF01091
PRINTS PR00269
PIRSF
SMART SM00193
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21741
PhosphoSite PhosphoSite-P21741
TrEMBL
UniProt Splice Variant
Entrez Gene 4192
UniGene
RefSeq NP_001257481
HUGO HGNC:6972
OMIM 162096
CCDS CCDS59226
HPRD 01200
IMGT
EMBL AC116021 BC011704 D10604 DQ323888 M69148 M94250 X55110
GenPept AAA58478 AAA59850 AAH11704 ABC55425 BAA01457 CAA38908