InnateDB Protein
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IDBP-239305.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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UPP1
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Protein Name
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uridine phosphorylase 1
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Synonyms
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UDRPASE; UP; UPASE; UPP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378927
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InnateDB Gene
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IDBG-16202 (UPP1)
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Protein Structure
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Function |
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
10
[view]
|
Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004850
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uridine phosphorylase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q16831
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PhosphoSite |
PhosphoSite-Q16831
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
7378
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UniGene |
Hs.488240
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RefSeq |
NP_001274358
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HUGO |
HGNC:12576
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OMIM |
191730
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CCDS |
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HPRD |
08932
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IMGT |
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EMBL |
BC001405
BC007348
BC053592
BT006699
CH471128
X90858
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GenPept |
AAH01405
AAH07348
AAH53592
AAP35345
CAA62369
CAA62370
EAW60994
EAW60995
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