InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MAPK10

Summary

InnateDB Protein

IDBP-240100.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAPK10

Protein Name

mitogen-activated protein kinase 10

Synonyms

JNK3; JNK3A; p493F12; p54bSAPK; PRKM10; SAPK1b;

Species

Homo sapiens

Ensembl Protein

ENSP00000378586

InnateDB Gene

IDBG-28343 (MAPK10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	67 [view]
Protein-Protein	67 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004707	MAP kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000165	MAPK cascade
GO:0006468	protein phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008351 Mitogen-activated protein (MAP) kinase, JNK
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714

PRINTS

PR00109
PR01772

PIRSF

SMART

SM00220

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt