Version 5.4
Homo sapiens Protein: TCF7
Summary
InnateDB Protein IDBP-240365.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCF7
Protein Name transcription factor 7 (T-cell specific, HMG-box)
Synonyms TCF-1;
Species Homo sapiens
Ensembl Protein ENSP00000378472
InnateDB Gene IDBG-44412 (TCF7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 7 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008013 beta-catenin binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0016055 Wnt signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
IPR013558 CTNNB1 binding, N-teminal
PFAM PF00505
PF09011
PF08347
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RJ51
UniProt Splice Variant
Entrez Gene 6932
UniGene Hs.688155
RefSeq XP_006714746
HUGO HGNC:11639
OMIM 189908
CCDS
HPRD 01797
IMGT
EMBL AC008608 AC011336 CH471062
GenPept EAW62279

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca