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InnateDB Protein
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IDBP-242585.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SYT12
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Protein Name
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synaptotagmin XII
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377520
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InnateDB Gene
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IDBG-59801 (SYT12)
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Protein Structure
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| Function |
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}.
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| Subcellular Localization |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
1
[view]
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| Protein-Protein |
1
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR000008
C2 domain
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| PFAM |
PF00168
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| PRINTS |
PR00360
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| PIRSF |
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| SMART |
SM00239
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q8IV01
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| PhosphoSite |
PhosphoSite-Q8IV01
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| TrEMBL |
Q8NDM9
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| UniProt Splice Variant |
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| Entrez Gene |
91683
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| UniGene |
Hs.287636
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| RefSeq |
XP_006718800
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| HUGO |
HGNC:18381
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| OMIM |
606436
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| CCDS |
CCDS8154
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| HPRD |
07337
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| IMGT |
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| EMBL |
AL833834
AP000729
AP003176
BC037406
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| GenPept |
AAH37406
CAD38694
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