Homo sapiens Protein: SYT12
Summary
InnateDB Protein IDBP-242585.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYT12
Protein Name synaptotagmin XII
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377520
InnateDB Gene IDBG-59801 (SYT12)
Protein Structure
UniProt Annotation
Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
PFAM PF00168
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IV01
PhosphoSite PhosphoSite-Q8IV01
TrEMBL Q8NDM9
UniProt Splice Variant
Entrez Gene 91683
UniGene Hs.287636
RefSeq XP_006718800
HUGO HGNC:18381
OMIM 606436
CCDS CCDS8154
HPRD 07337
IMGT
EMBL AL833834 AP000729 AP003176 BC037406
GenPept AAH37406 CAD38694