InnateDB Protein
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IDBP-243544.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LIPT1
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Protein Name
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lipoyltransferase 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377115
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InnateDB Gene
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IDBG-63192 (LIPT1)
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Protein Structure
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Function |
Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes. {ECO:0000250}.
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Subcellular Localization |
Mitochondrion.
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Disease Associations |
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Tissue Specificity |
Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung. {ECO:0000269PubMed:10103005}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004143
Biotin/lipoate A/B protein ligase
IPR004562
Lipoyltransferase/lipoate-protein ligase
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PFAM |
PF03099
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y234
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PhosphoSite |
PhosphoSite-Q9Y234
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TrEMBL |
C9JW10
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UniProt Splice Variant |
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Entrez Gene |
51601
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UniGene |
Hs.739177
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RefSeq |
NP_660199
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HUGO |
HGNC:29569
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OMIM |
610284
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CCDS |
CCDS2039
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HPRD |
17282
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IMGT |
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EMBL |
AB017566
AB017567
AC092587
BC007001
BC009772
BC070145
CH471127
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GenPept |
AAH07001
AAH09772
AAH70145
AAX88927
BAA76367
BAA76368
EAX01877
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