Version 5.4
Homo sapiens Protein: PTN
Summary
InnateDB Protein IDBP-244342.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTN
Protein Name pleiotrophin
Synonyms HARP; HBGF8; HBNF; NEGF1;
Species Homo sapiens
Ensembl Protein ENSP00000376798
InnateDB Gene IDBG-42963 (PTN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 116 [view]
Protein-Protein 114 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000762 Midkine heparin-binding growth factor
IPR020089 Pleiotrophin/Midkine, N-terminal domain
IPR020090 Pleiotrophin/Midkine, C-terminal domain
IPR020091 Pleiotrophin/Midkine disulphide-rich domain
PFAM PF05196
PF01091
PRINTS PR00269
PIRSF
SMART SM00193
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JR52
UniProt Splice Variant
Entrez Gene 5764
UniGene Hs.713732
RefSeq
HUGO HGNC:9630
OMIM 162095
CCDS
HPRD 01199
IMGT
EMBL AC018728 AC078842
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca