InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BDH1

Summary

InnateDB Protein

IDBP-245778.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BDH1

Protein Name

3-hydroxybutyrate dehydrogenase, type 1

Synonyms

BDH; SDR9C1;

Species

Homo sapiens

Ensembl Protein

ENSP00000376184

InnateDB Gene

IDBG-71705 (BDH1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003858	3-hydroxybutyrate dehydrogenase activity
GO:0005543	phospholipid binding
GO:0016491	oxidoreductase activity

Biological Process

GO:0001889	liver development
GO:0007420	brain development
GO:0007584	response to nutrient
GO:0008152	metabolic process
GO:0009636	response to toxic substance
GO:0009725	response to hormone
GO:0032355	response to estradiol
GO:0032868	response to insulin
GO:0042493	response to drug
GO:0042594	response to starvation
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0045471	response to ethanol
GO:0046686	response to cadmium ion
GO:0046950	cellular ketone body metabolic process
GO:0046951	ketone body biosynthetic process
GO:0046952	ketone body catabolic process
GO:0051412	response to corticosterone
GO:0055114	oxidation-reduction process
GO:0060416	response to growth hormone
GO:0060612	adipose tissue development

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR013968 Polyketide synthase, KR

PFAM

PF00106
PF08659

PRINTS

PR00080
PR00081
PR01397

PIRSF

PIRSF000126

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt