InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vma21

Summary

InnateDB Protein

IDBP-251483.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vma21

Protein Name

VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)

Synonyms

2610030H06Rik; AI840175;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110223

InnateDB Gene

IDBG-150898 (Vma21)

Protein Structure

UniProt Annotation

Function

Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. {ECO:0000255HAMAP-Rule:MF_03058}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000255HAMAP-Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP-Rule:MF_03058}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000255HAMAP- Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP- Rule:MF_03058}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000255HAMAP-Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP-Rule:MF_03058}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0070072

vacuolar proton-transporting V-type ATPase complex assembly

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane
GO:0030127	COPII vesicle coat
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane