InnateDB Protein
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IDBP-252208.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gng12
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Protein Name
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guanine nucleotide binding protein (G protein), gamma 12
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Synonyms
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2010305F15Rik; AA536815; AI115529; AI314170; AI842738;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109865
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InnateDB Gene
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IDBG-153698 (Gng12)
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Protein Structure
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
12 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1336171
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InterPro |
IPR001770
G-protein, gamma subunit
IPR015898
G-protein gamma-like domain
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PFAM |
PF00631
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PRINTS |
PR00321
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PIRSF |
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SMART |
SM00224
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TIGRFAMs |
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Modification |
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SwissProt |
Q9DAS9
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PhosphoSite |
PhosphoSite-Q9DAS9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14701
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UniGene |
Mm.472558
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RefSeq |
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MGI ID |
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MGI Symbol |
Gng12
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OMIM |
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CCDS |
CCDS39502
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HPRD |
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IMGT |
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EMBL |
AK005561
AK033422
AK148765
AK159872
AK162342
AK166035
AK166299
BC040685
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GenPept |
AAH40685
BAB24121
BAC28280
BAE28660
BAE35445
BAE36863
BAE38536
BAE38688
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