InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tia1

Summary

InnateDB Protein

IDBP-253302.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Tia1

Protein Name

cytotoxic granule-associated RNA binding protein 1

Synonyms

2310050N03Rik; AI256674; mTIA-1; TIA-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109342

InnateDB Gene

IDBG-164670 (Tia1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0017091	AU-rich element binding

Biological Process

GO:0017148	negative regulation of translation
GO:0042036	negative regulation of cytokine biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0010494	cytoplasmic stress granule
GO:0097165	nuclear stress granule

Protein Structure and Domains

PDB ID

MGI:107914

InterPro

IPR000504 RNA recognition motif domain
IPR003954 RNA recognition motif domain, eukaryote

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360
SM00361

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q80ZW7

UniProt Splice Variant

Entrez Gene

21841

UniGene

Mm.488871

RefSeq

NP_001157550

MGI ID

MGI Symbol

Tia1

OMIM

CCDS

CCDS51834

HPRD

IMGT

EMBL

AC153374 BC046812

GenPept

AAH46812