InnateDB Protein
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IDBP-254079.5
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Last Modified
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2012-02-14 [Report errors or provide feedback]
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Gene Symbol
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Mitf
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Protein Name
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microphthalmia-associated transcription factor
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Synonyms
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BCC2; Bhlhe32; bw; Gsfbcc2; mi; vit; Vitiligo; Wh;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000108965
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InnateDB Gene
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IDBG-172461 (Mitf)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
11
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
2
[view]
|
RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
29 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0000979
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RNA polymerase II core promoter sequence-specific DNA binding
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GO:0003677
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DNA binding
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GO:0003682
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chromatin binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0003705
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RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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GO:0046983
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protein dimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:104554
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InterPro |
IPR011598
Myc-type, basic helix-loop-helix (bHLH) domain
IPR021802
Basic helix-loop-helix leucine zipper transcrition factor MiT/TFE
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PFAM |
PF00010
PF11851
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PRINTS |
|
PIRSF |
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SMART |
SM00353
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q5C9J0
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UniProt Splice Variant |
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Entrez Gene |
17342
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UniGene |
Mm.413799
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RefSeq |
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MGI ID |
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MGI Symbol |
Mitf
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC131676
AC157098
AC158650
AY632573
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GenPept |
AAV34582
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