InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pde6c

Summary

InnateDB Protein

IDBP-256236.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pde6c

Protein Name

phosphodiesterase 6C, cGMP specific, cone, alpha prime

Synonyms

cpfl1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107948

InnateDB Gene

IDBG-162765 (Pde6c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0030553	cGMP binding
GO:0046872	metal ion binding
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity

Biological Process

GO:0007165	signal transduction
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0008152	metabolic process
GO:0046549	retinal cone cell development
GO:0050953	sensory perception of light stimulus

Cellular Component

GO:0005886

plasma membrane

Protein Structure and Domains

PDB ID

MGI:105956

InterPro

IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003018 GAF domain
IPR003607 HD/PDEase domain
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
IPR029016 GAF domain-like

PFAM

PF00233
PF01590
PF13185
PF13492

PRINTS

PR00387

PIRSF

SMART

SM00065
SM00471

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt