Version 5.4
Mus musculus Protein: Ren1
Summary
InnateDB Protein IDBP-256325.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Ren1
Protein Name renin 1 structural
Synonyms D19352; Ren; Ren-1; Ren-2; Ren-A; Ren-B; Ren1c; Ren1d; Rn-1; Rn-2; Rnr;
Species Mus musculus
Ensembl Protein ENSMUSP00000107906
InnateDB Gene IDBG-192844 (Ren1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
GO:0005159 insulin-like growth factor receptor binding
Biological Process
GO:0001822 kidney development
GO:0002003 angiotensin maturation
GO:0002016 regulation of blood volume by renin-angiotensin
GO:0002018 renin-angiotensin regulation of aldosterone production
GO:0006508 proteolysis
GO:0009755 hormone-mediated signaling pathway
GO:0010033 response to organic substance
GO:0032496 response to lipopolysaccharide
GO:0035690 cellular response to drug
GO:0042756 drinking behavior
GO:0043408 regulation of MAPK cascade
GO:0048469 cell maturation
GO:0050435 beta-amyloid metabolic process
GO:0051591 response to cAMP
GO:0070305 response to cGMP
Cellular Component
GO:0005615 extracellular space
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:97898
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9R259
UniProt Splice Variant
Entrez Gene 19702
UniGene
RefSeq
MGI ID
MGI Symbol Ren1
OMIM
CCDS
HPRD
IMGT
EMBL AC068906 AF117821
GenPept AAD26253

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca