InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmem27

Summary

InnateDB Protein

IDBP-256340.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmem27

Protein Name

transmembrane protein 27

Synonyms

0610008J07Rik; NX-17; NX17;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107899

InnateDB Gene

IDBG-184488 (Tmem27)

Protein Structure

UniProt Annotation

Function

Regulator of SNARE complex function. Stimulator of beta cell replication. {ECO:0000269PubMed:16330323, ECO:0000269PubMed:16330324}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Kidney; collecting ducts. Pancreas; beta cells of islets. {ECO:0000269PubMed:11278314, ECO:0000269PubMed:16330323, ECO:0000269PubMed:16330324}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008237	metallopeptidase activity
GO:0008241	peptidyl-dipeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0035543	positive regulation of SNARE complex assembly
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0051957	positive regulation of amino acid transport