InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Piga

Summary

InnateDB Protein

IDBP-256395.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Piga

Protein Name

phosphatidylinositol glycan anchor biosynthesis, class A

Synonyms

AI194334; Pig-a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107874

InnateDB Gene

IDBG-184835 (Piga)

Protein Structure

UniProt Annotation

Function

Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.

Subcellular Localization

Endoplasmic reticulum membrane; Single-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016757	transferase activity, transferring glycosyl groups

Biological Process

GO:0006506	GPI anchor biosynthetic process
GO:0009058	biosynthetic process

Cellular Component

GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane