InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Actn2

Summary

InnateDB Protein

IDBP-259883.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Actn2

Protein Name

actinin alpha 2

Synonyms

1110008F24Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106246

InnateDB Gene

IDBG-129876 (Actn2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030274	LIM domain binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375	thyroid hormone receptor coactivator activity
GO:0030674	protein binding, bridging
GO:0051015	actin filament binding

Biological Process

GO:0006936	muscle contraction
GO:2000273	positive regulation of receptor activity
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0005865	striated muscle thin filament
GO:0030017	sarcomere
GO:0030018	Z disc

Protein Structure and Domains

PDB ID

MGI:109192

InterPro

IPR001715 Calponin homology domain

PFAM

PF00307

PRINTS

PIRSF

SMART

SM00033

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YY95

UniProt Splice Variant

Entrez Gene

11472

UniGene

Mm.37638

RefSeq

MGI ID

MGI Symbol

Actn2

OMIM

CCDS

HPRD

IMGT

EMBL

AC154523

GenPept