InnateDB Protein
|
IDBP-267153.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Psip1
|
Protein Name
|
PC4 and SFRS1 interacting protein 1
|
Synonyms
|
AA408851; AU015605; Dfs70; Ledgfa; Ledgfb; Psip2;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000102833
|
InnateDB Gene
|
IDBG-160130 (Psip1)
|
Protein Structure
|
|
Function |
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Nucleus {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated |
Total |
9
[view]
|
Protein-Protein |
9
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
35 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2142116
|
InterPro |
IPR000313
PWWP domain
|
PFAM |
PF00855
|
PRINTS |
|
PIRSF |
|
SMART |
SM00293
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q99JF8
|
PhosphoSite |
PhosphoSite-Q99JF8
|
TrEMBL |
F6RB63
|
UniProt Splice Variant |
|
Entrez Gene |
101739
|
UniGene |
Mm.455389
|
RefSeq |
NP_001277456
|
MGI ID |
|
MGI Symbol |
Psip1
|
OMIM |
|
CCDS |
CCDS71412
|
HPRD |
|
IMGT |
|
EMBL |
AF339082
AF339083
AJ308965
AJ308966
AK011572
AK139598
AK161426
AK169600
BC002260
BC043079
BC052177
BX682545
|
GenPept |
AAH02260
AAH43079
AAH52177
AAO32949
AAO32950
BAB27707
BAE24079
BAE36388
BAE41251
CAC34944
CAC34945
CAM20466
CAM20467
|
|
|