InnateDB Protein
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IDBP-2673.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DDT
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Protein Name
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D-dopachrome tautomerase
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Synonyms
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DDCT;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000215773
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InnateDB Gene
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IDBG-2671 (DDT)
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Protein Structure
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Function |
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
Accession |
GO Term |
GO:0004167
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dopachrome isomerase activity
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GO:0033981
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D-dopachrome decarboxylase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001398
Macrophage migration inhibitory factor
IPR014347
Tautomerase/MIF superfamily
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PFAM |
PF01187
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P30046
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PhosphoSite |
PhosphoSite-P30046
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TrEMBL |
Q53Y51
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UniProt Splice Variant |
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Entrez Gene |
1652
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UniGene |
|
RefSeq |
NP_001346
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HUGO |
HGNC:2732
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OMIM |
602750
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CCDS |
CCDS13820
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HPRD |
04126
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IMGT |
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EMBL |
AF012432
AF012433
AF012434
AF058293
AK292044
BC005971
BC015508
BT006970
CH471095
CR456431
U49785
U84143
Y11151
Z84718
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GenPept |
AAB41503
AAB48546
AAC13717
AAC77468
AAH05971
AAH15508
AAP35616
BAF84733
CAA72037
CAG30317
EAW59623
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