Homo sapiens Gene: DDT
Summary
InnateDB Gene IDBG-2671.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDT
Gene Name D-dopachrome tautomerase
Synonyms DDCT;
Species Homo sapiens
Ensembl Gene ENSG00000099977
Encoded Proteins
D-dopachrome tautomerase
D-dopachrome tautomerase
D-dopachrome tautomerase
D-dopachrome tautomerase
D-dopachrome tautomerase
D-dopachrome tautomerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:23971365-23980469
Strand Reverse strand
Band q11.23
Transcripts
ENST00000350608 ENSP00000215773
ENST00000398344 ENSP00000381386
ENST00000404092 ENSP00000385714
ENST00000403754 ENSP00000384866
ENST00000428792 ENSP00000409440
ENST00000430101 ENSP00000399768
ENST00000444947
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004167 dopachrome isomerase activity
GO:0033981 D-dopachrome decarboxylase activity
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL B7Z522
UniProt Splice Variant
Entrez Gene 1652
UniGene
RefSeq NM_001355 NM_001084392 XM_006725406
HUGO HGNC:2732
OMIM 602750
CCDS CCDS13820
HPRD 04126
IMGT
EMBL AK298326 AP000351 CH471095
GenPept BAH12758 EAW59622
RNA Seq Atlas 100037417 1652