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InnateDB Protein
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IDBP-268007.5
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Last Modified
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2012-02-14 [Report errors or provide feedback]
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Gene Symbol
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Ern1
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Protein Name
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endoplasmic reticulum (ER) to nucleus signalling 1
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Synonyms
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9030414B18Rik; AI225830; C85377; Ire1a; Ire1alpha; Ire1p;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000102412
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InnateDB Gene
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IDBG-213476 (Ern1)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
5
[view]
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| Protein-Protein |
5
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
15 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0004521
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endoribonuclease activity
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| Biological Process |
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GO:0030968
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endoplasmic reticulum unfolded protein response
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GO:0045087
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innate immune response (InnateDB)
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GO:0046777
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protein autophosphorylation
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GO:0070059
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intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
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GO:0090502
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RNA phosphodiester bond hydrolysis, endonucleolytic
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| Cellular Component |
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| PDB ID |
MGI:1930134
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| InterPro |
IPR011047
Quinonprotein alcohol dehydrogenase-like superfamily
IPR018391
Pyrrolo-quinoline quinone beta-propeller repeat
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
SM00564
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
B1ARJ5
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| UniProt Splice Variant |
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| Entrez Gene |
78943
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| UniGene |
Mm.403353
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Ern1
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL604045
AL663053
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| GenPept |
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Version 5.4