InnateDB Protein
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IDBP-268009.5
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Last Modified
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2012-02-14 [Report errors or provide feedback]
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Gene Symbol
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Ern1
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Protein Name
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endoplasmic reticulum (ER) to nucleus signalling 1
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Synonyms
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9030414B18Rik; AI225830; C85377; Ire1a; Ire1alpha; Ire1p;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000102411
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InnateDB Gene
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IDBG-213476 (Ern1)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
15 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004521
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endoribonuclease activity
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Biological Process |
GO:0030968
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endoplasmic reticulum unfolded protein response
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GO:0045087
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innate immune response (InnateDB)
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GO:0046777
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protein autophosphorylation
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GO:0070059
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intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
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GO:0090502
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RNA phosphodiester bond hydrolysis, endonucleolytic
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Cellular Component |
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PDB ID |
MGI:1930134
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InterPro |
IPR011047
Quinonprotein alcohol dehydrogenase-like superfamily
IPR018391
Pyrrolo-quinoline quinone beta-propeller repeat
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00564
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
B1ATQ7
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UniProt Splice Variant |
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Entrez Gene |
78943
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UniGene |
Mm.403353
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RefSeq |
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MGI ID |
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MGI Symbol |
Ern1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL604045
AL663053
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GenPept |
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