Version 5.4
Mus musculus Protein: Hgs
Summary
InnateDB Protein IDBP-269251.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Hgs
Protein Name HGF-regulated tyrosine kinase substrate
Synonyms Hgr; Hrs; ZFYVE8;
Species Mus musculus
Ensembl Protein ENSMUSP00000101811
InnateDB Gene IDBG-214821 (Hgs)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 138 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 138 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:104681
InterPro IPR000306 FYVE zinc finger
IPR002014 VHS
IPR003903 Ubiquitin interacting motif
IPR008942 ENTH/VHS
IPR011011 Zinc finger, FYVE/PHD-type
IPR017073 Ubiquitin binding protein, Hrs/VPS27
IPR017455 Zinc finger, FYVE-related
IPR018205 VHS subgroup
IPR024641 Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain
PFAM PF01363
PF00790
PF02809
PF12210
PRINTS
PIRSF PIRSF036956
SMART SM00064
SM00726
SM00288
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1ATZ0
UniProt Splice Variant
Entrez Gene 15239
UniGene
RefSeq
MGI ID
MGI Symbol Hgs
OMIM
CCDS
HPRD
IMGT
EMBL AL669855
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca