InnateDB Protein
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IDBP-26931.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SNX16
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Protein Name
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sorting nexin 16
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000322631
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InnateDB Gene
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IDBG-26927 (SNX16)
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Protein Structure
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Function |
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. {ECO:0000269PubMed:12813048, ECO:0000269PubMed:15951806}.
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Subcellular Localization |
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm {ECO:0000250}. Lysosome {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detected in placenta, lung, liver,heart and pancreas. {ECO:0000269PubMed:12813048}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001683
Phox homologous domain
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PFAM |
PF00787
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PRINTS |
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PIRSF |
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SMART |
SM00312
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TIGRFAMs |
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Modification |
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SwissProt |
P57768
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PhosphoSite |
PhosphoSite-P57768
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TrEMBL |
E5RJ81
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UniProt Splice Variant |
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Entrez Gene |
64089
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UniGene |
Hs.610480
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RefSeq |
NP_690050
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HUGO |
HGNC:14980
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OMIM |
614903
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CCDS |
CCDS6235
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HPRD |
15411
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IMGT |
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EMBL |
AC087349
AC132219
AF305779
AK290903
AL833763
BC033630
CH471068
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GenPept |
AAG25676
AAH33630
BAF83592
CAH56235
EAW87108
EAW87109
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