Version 5.4
Homo sapiens Gene: SNX16
Summary
InnateDB Gene IDBG-26927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX16
Gene Name sorting nexin 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104497
Encoded Proteins
IDBP-26929
sorting nexin 16
IDBP-26931
sorting nexin 16
IDBP-237762
sorting nexin 16
IDBP-476392
sorting nexin 16
IDBP-484740
sorting nexin 16
IDBP-476499
sorting nexin 16
IDBP-475216
sorting nexin 16
IDBP-483880
sorting nexin 16
IDBP-474799
sorting nexin 16
IDBP-482235
sorting nexin 16
IDBP-811347
sorting nexin 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The function of this protein has not been determined. This gene results in three transcript variants encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:81799581-81842866
Strand Reverse strand
Band q21.13
Transcripts
ENST00000345957 ENSP00000322652
ENST00000353788 ENSP00000322631
ENST00000396330 ENSP00000379621
ENST00000520618 ENSP00000428699
ENST00000519212
ENST00000523757 ENSP00000430038
ENST00000521810 ENSP00000428734
ENST00000519119 ENSP00000427876
ENST00000519817 ENSP00000428591
ENST00000518183 ENSP00000428289
ENST00000521773 ENSP00000430585
ENST00000615066 ENSP00000481148
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
Biological Process
GO:0006622 protein targeting to lysosome
GO:0008333 endosome to lysosome transport
GO:0045022 early endosome to late endosome transport
Cellular Component
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0031313 extrinsic component of endosome membrane
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027534
View Gene Order
ENSBTAG00000019639
Not yet available
Cross-References
SwissProt P57768
TrEMBL E5RGQ6 E5RHF1 E5RJ65 E5RJ81
UniProt Splice Variant
Entrez Gene 64089
UniGene Hs.492121 Hs.610480
RefSeq NM_022133 NM_152836 NM_152837 XM_005251284
HUGO HGNC:14980
OMIM 614903
CCDS CCDS6234 CCDS6235
HPRD 15411
IMGT
EMBL AC087349 AC132219 AF305779 AK290903 AL833763 BC033630 CH471068
GenPept AAG25676 AAH33630 BAF83592 CAH56235 EAW87108 EAW87109
RNA Seq Atlas 64089

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca