InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufs7

Summary

InnateDB Protein

IDBP-271033.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufs7

Protein Name

NADH dehydrogenase (ubiquinone) Fe-S protein 7

Synonyms

1010001M04Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101003

InnateDB Gene

IDBG-173377 (Ndufs7)

Protein Structure

UniProt Annotation

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0003954	NADH dehydrogenase activity
GO:0005515	protein binding
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0046872	metal ion binding
GO:0048038	quinone binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

Biological Process

GO:0032981	mitochondrial respiratory chain complex I assembly
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0097060	synaptic membrane