InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BCKDK

Summary

InnateDB Protein

IDBP-27750.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BCKDK

Protein Name

branched chain ketoacid dehydrogenase kinase

Synonyms

BCKDKD; BDK;

Species

Homo sapiens

Ensembl Protein

ENSP00000287507

InnateDB Gene

IDBG-27748 (BCKDK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.

Experimentally validated
Total	20 [view]
Protein-Protein	18 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0047323	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity

Biological Process

GO:0009063	cellular amino acid catabolic process
GO:0009083	branched-chain amino acid catabolic process
GO:0016310	phosphorylation

Cellular Component

GO:0005739	mitochondrion
GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex

Protein Structure and Domains

PDB ID

InterPro

IPR003594 Histidine kinase-like ATPase, C-terminal domain
IPR018955 Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal

PFAM

PF02518
PF13581
PF10436

PRINTS

PIRSF

SMART

SM00387

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O14874