Version 5.4
Homo sapiens Protein: SPIRE1
Summary
InnateDB Protein IDBP-292517.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPIRE1
Protein Name spire homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387266
InnateDB Gene IDBG-1137 (SPIRE1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0030036 actin cytoskeleton organization
GO:0036089 cleavage furrow formation
GO:0040038 polar body extrusion after meiotic divisions
GO:0046907 intracellular transport
GO:0048193 Golgi vesicle transport
GO:0051295 establishment of meiotic spindle localization
GO:0070649 formin-nucleated actin cable assembly
Cellular Component
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0030659 cytoplasmic vesicle membrane
GO:0032154 cleavage furrow
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR011011 Zinc finger, FYVE/PHD-type
IPR011019 KIND
PFAM
PRINTS
PIRSF
SMART SM00750
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08AE8
PhosphoSite PhosphoSite-Q08AE8
TrEMBL Q96AS4
UniProt Splice Variant
Entrez Gene 56907
UniGene Hs.708220
RefSeq NP_001122098
HUGO HGNC:30622
OMIM 609216
CCDS CCDS45829
HPRD 11600
IMGT
EMBL AB032961 AJ277587 AK290180 AL833817 AP001028 AP001029 AP005482 BC016825 BC115005 BC125206 BC125207 CH471113
GenPept AAH16825 AAI15006 AAI25207 AAI25208 BAA86449 BAF82869 CAB96370 CAD38680 EAX01546

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca