InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SCLY

Summary

InnateDB Protein

IDBP-292857.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCLY

Protein Name

selenocysteine lyase

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000387162

InnateDB Gene

IDBG-84394 (SCLY)

Protein Structure

UniProt Annotation

Function

Catalyzes the decomposition of L-selenocysteine to L- alanine and elemental selenium. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0009000	selenocysteine lyase activity
GO:0016740	transferase activity
GO:0016829	lyase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0006520	cellular amino acid metabolic process
GO:0008152	metabolic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR000192 Aminotransferase class V domain
IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase
IPR015424 Pyridoxal phosphate-dependent transferase
IPR016454 Cysteine desulfurase, NifS

PFAM

PF00266
PF01212

PRINTS

PIRSF

PIRSF005572

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96I15