InnateDB Protein
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IDBP-293377.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PPP1R1C
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Protein Name
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protein phosphatase 1, regulatory (inhibitor) subunit 1C
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000386778
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InnateDB Gene
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IDBG-76815 (PPP1R1C)
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Protein Structure
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Function |
Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis. {ECO:0000269PubMed:18310074, ECO:0000269PubMed:19874272}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in heart, skeletal muscle, liver and testis (at protein level).
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0004864
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protein phosphatase inhibitor activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008466
Protein phosphatase inhibitor, 1DARPP-32
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PFAM |
PF05395
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8WVI7
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PhosphoSite |
PhosphoSite-Q8WVI7
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TrEMBL |
Q53TF4
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UniProt Splice Variant |
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Entrez Gene |
151242
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UniGene |
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RefSeq |
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HUGO |
HGNC:14940
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OMIM |
613240
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CCDS |
CCDS46468
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HPRD |
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IMGT |
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EMBL |
AC009962
AC064837
AF494535
BC017943
BX647581
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GenPept |
AAH17943
AAM18054
AAY14914
AAY24129
CAI46089
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