Version 5.4
Homo sapiens Gene: PPP1R1C
Summary
InnateDB Gene IDBG-76815.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R1C
Gene Name protein phosphatase 1, regulatory (inhibitor) subunit 1C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000150722
Encoded Proteins
IDBP-76817
protein phosphatase 1, regulatory (inhibitor) subunit 1C
IDBP-293373
protein phosphatase 1, regulatory (inhibitor) subunit 1C
IDBP-293377
protein phosphatase 1, regulatory (inhibitor) subunit 1C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:181954241-182131398
Strand Forward strand
Band q31.3
Transcripts
ENST00000280295 ENSP00000280295
ENST00000409137 ENSP00000386359
ENST00000409702 ENSP00000386778
ENST00000495820
ENST00000486067
ENST00000475249
ENST00000464264
ENST00000490645
ENST00000465612
ENST00000479855
ENST00000461410
ENST00000494189
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
Biological Process
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0030307 positive regulation of cell growth
GO:0043086 negative regulation of catalytic activity
GO:0051301 cell division
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034683
View Gene Order
ENSBTAG00000044009
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001080545 NM_001261424 NM_001261425
HUGO
OMIM
CCDS CCDS46468 CCDS58740
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca