InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TPT1

Summary

InnateDB Protein

IDBP-29342.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TPT1

Protein Name

tumor protein, translationally-controlled 1

Synonyms

HRF; p02; p23; TCTP;

Species

Homo sapiens

Ensembl Protein

ENSP00000339051

InnateDB Gene

IDBG-29334 (TPT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	51 [view]
Protein-Protein	48 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006816	calcium ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0009615	response to virus
GO:0042981	regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005771	multivesicular body
GO:0045298	tubulin complex

Protein Structure and Domains

PDB ID

InterPro

IPR011057 Mss4-like
IPR018105 Translationally controlled tumour protein

PFAM

PF00838

PRINTS

PR01653

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AJ400717 AK312951 AL138963 AY117678 AY334563 BC003352 BC012431 BC022436 BC040008 BC052333 CH471075 CR457036 X16064

GenPept

AAH03352 AAH12431 AAH22436 AAH40008 AAH52333 AAM51565 AAQ01550 BAG35792 CAA34200 CAB87812 CAG33317 CAH72034 EAX08731 EAX08732 EAX08735

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca