InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: TPT1

Summary

InnateDB Gene

IDBG-29334.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TPT1

Gene Name

tumor protein, translationally-controlled 1

Synonyms

HRF; p02; p23; TCTP

Species

Homo sapiens

Ensembl Gene

ENSG00000133112

Encoded Proteins

IDBP-29336

tumor protein, translationally-controlled 1

IDBP-29338

tumor protein, translationally-controlled 1

IDBP-29340

tumor protein, translationally-controlled 1

IDBP-29342

tumor protein, translationally-controlled 1

IDBP-589239

tumor protein, translationally-controlled 1

IDBP-593212

tumor protein, translationally-controlled 1

IDBP-593786

tumor protein, translationally-controlled 1

IDBP-590608

tumor protein, translationally-controlled 1

IDBP-808666

tumor protein, translationally-controlled 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:45333471-45341370

Strand

Reverse strand

Band

q14.13

Transcripts

ENST00000379060	ENSP00000368350
ENST00000379056	ENSP00000368345
ENST00000379055	ENSP00000368344
ENST00000309246	ENSP00000339051
ENST00000442760
ENST00000484604
ENST00000490277
ENST00000528619	ENSP00000433091
ENST00000529421
ENST00000533567
ENST00000530245	ENSP00000432457
ENST00000530705	ENSP00000431872
ENST00000527226	ENSP00000433738
ENST00000616577	ENSP00000477781

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	51 [view]
Protein-Protein	48 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006816	calcium ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0009615	response to virus
GO:0019827	stem cell maintenance
GO:0042981	regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0045087	innate immune response
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000384	negative regulation of ectoderm development

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005771	multivesicular body
GO:0045298	tubulin complex

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000060126

View Gene Order

ENSBTAG00000010156

Not yet available

Pathways

NETPATH

REACTOME

KEGG

INOH

PID NCI

plk1_pathway

PLK1 signaling events

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.520016 Hs.597818 Hs.702075 Hs.728858

RefSeq

NM_001286272 NM_001286273 NM_003295

HUGO

OMIM

CCDS

CCDS66538 CCDS73566 CCDS9397

HPRD

15979

IMGT

EMBL

GenPept

RNA Seq Atlas