Version 5.4
Homo sapiens Protein: IL1RL1
Summary
InnateDB Protein IDBP-295113.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL1RL1
Protein Name interleukin 1 receptor-like 1
Synonyms DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1;
Species Homo sapiens
Ensembl Protein ENSP00000384822
InnateDB Gene IDBG-64166 (IL1RL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 10 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0004908 interleukin-1 receptor activity
GO:0005057 receptor signaling protein activity
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS PR01536
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q01638
PhosphoSite PhosphoSite-Q01638
TrEMBL A8VPW9
UniProt Splice Variant
Entrez Gene 9173
UniGene Hs.731651
RefSeq NP_001269337
HUGO HGNC:5998
OMIM 601203
CCDS CCDS74548
HPRD 03123
IMGT
EMBL AB012701 AB029084 AC007248 AK291578 AK303389 BC030975 CH471127 D12763 D12764 EU181431
GenPept AAH30975 AAY15047 ABW33704 BAA02233 BAA20539 BAA82405 BAA85894 BAF84267 BAG64445 EAX01795

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca